literature_to_hypothesis
Extracts falsifiable scientific hypotheses (if-then form) from multiple PubMed articles, abstracts, or full texts. Synthesizes supporting evidence, contradictions, and experimental validation suggestions into a structured Markdown report for hypothesis-driven research planning.
npx skills add BioTender-max/awesome-bio-agent-skills --skill literature_to_hypothesis --agent claude-code
Same command for any agent — swap --agent for codex, cursor, copilot.
Weekly change comes from our own snapshots, not the repository page — it measures attention, not adoption.
# Literature to Hypothesis ## Overview `literature_to_hypothesis` distills the implicit and explicit hypotheses embedded in scientific literature into a structured, actionable format. Given multiple PubMed articles, abstracts, or full-text papers, it identifies testable if-then propositions, catalogs supporting and contradicting evidence across sources, and proposes concrete experimental validation strategies. The output is a Markdown report with hypothesis tables, evidence summaries, contradiction matrices, and validation roadmaps — enabling researchers to move from literature synthesis to hypothesis-driven experiment design in a single step, bridging the gap between "what we know" and "what we should test next." ## When to Use This Skill Use this skill when any of the following conditions are present: - **Literature-driven hypothesis extraction**: A researcher has collected 5–50 papers on a topic and wants to systematically extract the testable hypotheses that emerge from or are implied by the literature. - **Gap analysis and validation planning**: Identify which hypotheses in the literature are well-supported vs. under-tested; generate a prioritized list of experiments to valida
- Overview
- When to Use This Skill
- Core Capabilities
- 1. Literature Ingestion & Preprocessing
- 2. Hypothesis Extraction & Formulation
- 3. Evidence Synthesis
- 4. Contradiction Analysis
- 5. Experimental Validation Suggestions
- 6. Structured Markdown Report Output
- Usage Examples
- Example 1 — PubMed PMID List to Hypothesis Report
- Example 2 — Contradiction Synthesis
- Example 3 — Full-Text PDFs to Validation Roadmap
- Integration Notes
What does the literature_to_hypothesis skill do?
Extracts falsifiable scientific hypotheses (if-then form) from multiple PubMed articles, abstracts, or full texts. Synthesizes supporting evidence, contradictions, and experimental validation suggestions into a structured Markdown report for hypothesis-driven research planning.
How do I install it?
Run `npx skills add BioTender-max/awesome-bio-agent-skills --skill literature_to_hypothesis --agent claude-code` — it drops the skill into your project so the agent can pick it up. Swap the --agent value for codex, cursor or copilot if you use one of those.
Where does this skill come from?
From BioTender-max/awesome-bio-agent-skills, a repository with 135 stars. We read it straight from the repository tree rather than a submitted listing, so what you see here is what is actually published.
Is a popular skill a good skill?
Not necessarily. Stars measure attention, not adoption — a repository can trend for a week and be abandoned. That is why we show the weekly change from our own snapshots next to the total, instead of a single flattering number.