Agent skill · Workflow & Productivity

hypogenic

Plans and audits use of ChicagoHAI HypoGeniC/HypoRefine for LLM-assisted hypothesis generation from labeled text datasets. Use for the `hypogenic` package, its task configs, hypothesis banks, or HypoBench datasets—not for manual hypothesis formulation or scientific validation.

K-Dense-AIgithub.com/K-Dense-AIGitHub ↗
claude-codecan modify filesships scriptsMIT
Install
npx skills add K-Dense-AI/scientific-agent-skills --skill hypogenic --agent claude-code

Same command for any agent — swap --agent for codex, cursor, copilot.

Facts
Files in the skill folder: 18
SKILL.md size: 11 KB
Bundled scripts: yes
Version: 1.1
Allowed tools: ReadWriteEditBashGlobGrep
Requires: Requires Python 3.10+ and uv for the pinned upstream package. Bundled local audit tools use only the Python standard…
Path: skills/hypogenic/SKILL.md
Open the folder on GitHub →
Where it comes from
Stars: 32,619
Language: Python
Read our review of the source →

Weekly change comes from our own snapshots, not the repository page — it measures attention, not adoption.

From the SKILL.md

# HypoGeniC ## Scope and scientific boundary This skill covers the ChicagoHAI software repository `ChicagoHAI/hypothesis-generation` and PyPI package `hypogenic`. HypoGeniC iteratively proposes and scores textual patterns from labeled data; HypoRefine adds literature-derived information; union workflows combine banks. Keep these boundaries explicit: - The output is a bank of **candidate textual hypotheses and task-prediction statistics**. It is not experimental confirmation, causal evidence, a clinical conclusion, or proof of scientific novelty. - Predictive accuracy on held-out examples assesses task utility, not truth of a mechanism. Independent scientific validation still needs domain review, suitable controls, preregistered tests where appropriate, and new evidence. - For researcher-led formulation of mechanisms and falsifiable predictions, use `../hypothesis-generation/SKILL.md`. For open-ended ideation, use the scientific brainstorming skill. ## Default workflow: local review first Never start a model call automatically. 1. Classify the request: HypoGeniC software use, general hypothesis formulation, or downstream scientific validation. 2. Record the exact package, source, da

What's inside
Steps it walks through
  1. Scope and scientific boundary
  2. Default workflow: local review first
  3. Reproducible installation
  4. Safe configuration
  5. Dataset and prompt-text safety
  6. Run and cost planning
  7. Upstream CLI and API facts
  8. Local output inspection
  9. Evaluation without model calls
  10. Provider privacy gate
  11. References
  12. Bundled local tools
Ships with 17 files
  • assets/dataset_manifest.example.json
  • assets/result.example.json
  • assets/run_config.example.json
  • assets/task_config.example.yaml
  • references/configuration.md
  • references/datasets.md
  • references/evaluation.md
  • references/security.md
  • references/sources.md
  • references/upstream.md
  • scripts/__init__.py
  • scripts/_common.py
  • scripts/audit_dataset.py
  • scripts/evaluate_local.py
  • scripts/inspect_outputs.py
  • scripts/plan_run.py
  • scripts/validate_config.py
Commands it runs
uv venv --python 3.12 .venv
uv pip install "hypogenic==0.3.5"
python3 scripts/validate_config.py run \
uv run --with "pyyaml==6.0.2" \
python scripts/validate_config.py task \
python3 scripts/audit_dataset.py \
python3 scripts/plan_run.py \
hypogenic_generation --help
hypogenic_inference --help
python3 scripts/inspect_outputs.py hypotheses \
More from scientific-agent-skills
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About this skill
What does the hypogenic skill do?

Plans and audits use of ChicagoHAI HypoGeniC/HypoRefine for LLM-assisted hypothesis generation from labeled text datasets. Use for the `hypogenic` package, its task configs, hypothesis banks, or HypoBench datasets—not for manual hypothesis formulation or scientific validation.

How do I install it?

Run `npx skills add K-Dense-AI/scientific-agent-skills --skill hypogenic --agent claude-code` — it drops the skill into your project so the agent can pick it up. Swap the --agent value for codex, cursor or copilot if you use one of those.

Where does this skill come from?

From K-Dense-AI/scientific-agent-skills, a repository with 32,619 stars. We read it straight from the repository tree rather than a submitted listing, so what you see here is what is actually published.

Is a popular skill a good skill?

Not necessarily. Stars measure attention, not adoption — a repository can trend for a week and be abandoned. That is why we show the weekly change from our own snapshots next to the total, instead of a single flattering number.

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