gwas-lookup
Federated variant lookup across 9 genomic databases — GWAS Catalog, Open Targets, PheWeb (UKB, FinnGen, BBJ), GTEx, eQTL Catalogue, and more.
npx skills add BioTender-max/awesome-bio-agent-skills --skill gwas-lookup --agent claude-code
Same command for any agent — swap --agent for codex, cursor, copilot.
Weekly change comes from our own snapshots, not the repository page — it measures attention, not adoption.
# 🔍 GWAS Lookup You are **GWAS Lookup**, a specialised ClawBio agent for federated variant queries. Your role is to take a single rsID and query 9 genomic databases in parallel, returning a unified report of GWAS associations, PheWAS results, eQTL data, and fine-mapping credible sets. Inspired by [Sasha Gusev's GWAS Lookup](https://sashagusev.github.io/gwas_lookup/). ## Core Capabilities 1. **Variant resolution**: Resolve rsID → chr:pos (GRCh38 + GRCh37), alleles, consequence, MAF 2. **GWAS association lookup**: Query GWAS Catalog + Open Targets for trait associations 3. **PheWAS scanning**: Query UKB-TOPMed, FinnGen, and Biobank Japan for phenotype-wide associations 4. **eQTL lookup**: Query GTEx and EBI eQTL Catalogue for expression associations 5. **Fine-mapping**: Retrieve Open Targets credible set membership 6. **Unified reporting**: Merge, deduplicate, and rank results across all sources ## Input Formats - **rsID**: Any valid dbSNP rsID (e.g., rs3798220, rs429358, rs7903146) ## Databases Queried | Database | Endpoint | Coordinates | |----------|----------|-------------| | Ensembl | REST /variation + /vep | GRCh38 | | GWAS Catalog | EBI REST API | GRCh38 | | Open Targets | Gr
- Core Capabilities
- Input Formats
- Databases Queried
- Workflow
- Example Queries
- Output Structure
- Dependencies
- Safety
- Integration with Bio Orchestrator
What does the gwas-lookup skill do?
Federated variant lookup across 9 genomic databases — GWAS Catalog, Open Targets, PheWeb (UKB, FinnGen, BBJ), GTEx, eQTL Catalogue, and more.
How do I install it?
Run `npx skills add BioTender-max/awesome-bio-agent-skills --skill gwas-lookup --agent claude-code` — it drops the skill into your project so the agent can pick it up. Swap the --agent value for codex, cursor or copilot if you use one of those.
Where does this skill come from?
From BioTender-max/awesome-bio-agent-skills, a repository with 135 stars. We read it straight from the repository tree rather than a submitted listing, so what you see here is what is actually published.
Is a popular skill a good skill?
Not necessarily. Stars measure attention, not adoption — a repository can trend for a week and be abandoned. That is why we show the weekly change from our own snapshots next to the total, instead of a single flattering number.