GDKD-query
Query the Gene-Drug Knowledge Database (GDKD) for variant-specific gene–drug associations in oncology. Use when the user asks about cancer genomic biomarkers, drug sensitivity/resistance by gene or variant, targetable mutations, or clinical evidence for cancer therapeutics.
npx skills add BioTender-max/awesome-bio-agent-skills --skill gdkd --agent claude-code
Same command for any agent — swap --agent for codex, cursor, copilot.
Weekly change comes from our own snapshots, not the repository page — it measures attention, not adoption.
# GDKD Query Skill Search canonical GDKD rows by drug or gene entity. Auto-detects input type by pattern: | Input Pattern | Detected As | Match Logic | |---|---|---| | `ABL1`, `EGFR` | Gene symbol | substring on `gene` | | `imatinib`, `erlotinib` | Drug name | substring on `drug` | | anything else | Free text | substring on `drug` OR `gene` | ## API | Function | Input | Returns | |---|---|---| | `load_gdkd(path)` | CSV path | `list[dict]` | | `search(rows, entity)` | single entity string | `list[dict]` | | `search_batch(rows, entities)` | list of entity strings | `dict[str, list[dict]]` | | `summarize(hits, entity)` | rows + label | compact text | | `to_json(hits)` | rows | `list[dict]` | ## Usage See `if __name__ == "__main__"` block in `example.py` for runnable examples. ## Data - **Source**: GDKD normalized full-package output - **Paper**: Dienstmann et al., *Cancer Discovery* 2015;5(2):118-123 - **Format**: CSV - **Columns**: `drug`, `gene`, `score`, `source` - **Path**: `resources_metadata/dti/GDKD/gdkd.csv` (default `DATA_PATH` in `example.py`)
- API
- Usage
- Data
What does the GDKD-query skill do?
Query the Gene-Drug Knowledge Database (GDKD) for variant-specific gene–drug associations in oncology. Use when the user asks about cancer genomic biomarkers, drug sensitivity/resistance by gene or variant, targetable mutations, or clinical evidence for cancer therapeutics.
How do I install it?
Run `npx skills add BioTender-max/awesome-bio-agent-skills --skill gdkd --agent claude-code` — it drops the skill into your project so the agent can pick it up. Swap the --agent value for codex, cursor or copilot if you use one of those.
Where does this skill come from?
From BioTender-max/awesome-bio-agent-skills, a repository with 135 stars. We read it straight from the repository tree rather than a submitted listing, so what you see here is what is actually published.
Is a popular skill a good skill?
Not necessarily. Stars measure attention, not adoption — a repository can trend for a week and be abandoned. That is why we show the weekly change from our own snapshots next to the total, instead of a single flattering number.