ddinter-database
Query DDInter drug-drug interactions via REST API (1.7M+ interactions, 2,400+ drugs). Search by drug name/ID for severity (major/moderate/minor), mechanisms, and clinical recommendations. No auth. For FDA labeling use dailymed-database; for pharmacogenomics use clinpgx-database.
npx skills add BioTender-max/awesome-bio-agent-skills --skill ddinter-database --agent claude-code
Same command for any agent — swap --agent for codex, cursor, copilot.
Weekly change comes from our own snapshots, not the repository page — it measures attention, not adoption.
# DDInter Drug-Drug Interaction Database ## Overview DDInter is an open, curated database of drug-drug interactions (DDIs) covering 2,400+ drugs and 1.7M+ pairwise interactions with structured severity levels (major, moderate, minor), mechanistic annotations, and clinical management recommendations. Access is provided via a JSON REST API at `https://ddinter.scbdd.com/api/` — no authentication or registration required. ## When to Use - Checking whether two co-administered drugs have a known interaction and its severity (major/moderate/minor) - Retrieving all known interactions for a given drug to support polypharmacy risk assessment - Identifying the mechanistic basis (pharmacokinetic vs. pharmacodynamic) of a drug-drug interaction - Screening a drug combination list for potential major interactions before clinical decision support - Building automated DDI checking pipelines for medication review or drug repurposing workflows - Analyzing the DDI network for a drug class (e.g., all major interactions for CYP3A4 substrates) - For FDA-approved drug labeling text (indications, dosage, contraindications) use `dailymed-database` - For pharmacogenomics interactions (CYP genotype-drug assoc
- Overview
- When to Use
- Prerequisites
- Quick Start
- Core API
- Query 1: Search Drug by Name
- Query 2: Get All Interactions for a Drug
- Query 3: Get Interaction Details by Interaction ID
- Query 4: Check Interaction Between Two Specific Drugs
- Query 5: Filter Interactions by Severity Level
- Query 6: Polypharmacy Screening for a Drug List
- Query 7: Visualize Interaction Network
- Key Concepts
- Severity Classification
pip install requests pandas matplotlib networkx
What does the ddinter-database skill do?
Query DDInter drug-drug interactions via REST API (1.7M+ interactions, 2,400+ drugs). Search by drug name/ID for severity (major/moderate/minor), mechanisms, and clinical recommendations. No auth. For FDA labeling use dailymed-database; for pharmacogenomics use clinpgx-database.
How do I install it?
Run `npx skills add BioTender-max/awesome-bio-agent-skills --skill ddinter-database --agent claude-code` — it drops the skill into your project so the agent can pick it up. Swap the --agent value for codex, cursor or copilot if you use one of those.
Where does this skill come from?
From BioTender-max/awesome-bio-agent-skills, a repository with 135 stars. We read it straight from the repository tree rather than a submitted listing, so what you see here is what is actually published.
Is a popular skill a good skill?
Not necessarily. Stars measure attention, not adoption — a repository can trend for a week and be abandoned. That is why we show the weekly change from our own snapshots next to the total, instead of a single flattering number.