topexpressinggenes
Identifies and visualizes the top expressing genes per cluster in T/B cells, followed by pathway enrichment analysis. Provides quick cluster characterization by highlighting the most highly expressed genes and their biological functions.
Profile →npx skills add majiayu000/claude-skill-registry --skill topexpressinggenes-pwwang-immunopipe-9c464846 --agent claude-code
Same command for any agent — swap --agent for codex, cursor, copilot.
Weekly change comes from our own snapshots, not the repository page — it measures attention, not adoption.
# TopExpressingGenes Process Configuration ## Purpose Identifies and visualizes the top expressing genes per cluster in T/B cells, followed by pathway enrichment analysis. Provides quick cluster characterization by highlighting the most highly expressed genes and their biological functions. ## When to Use - **After**: `SeuratClustering` and `TOrBCellSelection` processes - **Use cases**: Quick cluster characterization, identifying dominant gene programs, pathway enrichment - **Optional process**: Enable only when cluster-level expression profiling is needed ## Configuration Structure ### Process Enablement ```toml [TopExpressingGenes] cache = true ``` ### Input Specification ```toml [TopExpressingGenes.in] srtobj = ["SeuratClustering"] ``` **Note**: `srtobj` accepts the output from `SeuratClustering` or `SeuratSubClustering`. ## Environment Variables ### Core Parameters ```toml [TopExpressingGenes.envs] # Number of top expressing genes to identify per cluster n = 250 # Enrichment style enrich_style = "enrichr" # Options: "enrichr", "clusterprofiler" # Enrichment databases dbs = ["KEGG_2021_Human", "MSigDB_Hallmark_2020"] ``` ### Enrichment Plot Settings ```toml [TopExpressingGenes.e
- Purpose
- When to Use
- Configuration Structure
- Process Enablement
- Input Specification
- Environment Variables
- Core Parameters
- Enrichment Plot Settings
- Configuration Examples
- Minimal Configuration
- Top 10 Genes with Custom Databases
- Network Visualization
- Common Patterns
- Pattern 1: Quick Cluster Overview
What does the topexpressinggenes skill do?
Identifies and visualizes the top expressing genes per cluster in T/B cells, followed by pathway enrichment analysis. Provides quick cluster characterization by highlighting the most highly expressed genes and their biological functions.
How do I install it?
Run `npx skills add majiayu000/claude-skill-registry --skill topexpressinggenes-pwwang-immunopipe-9c464846 --agent claude-code` — it drops the skill into your project so the agent can pick it up. Swap the --agent value for codex, cursor or copilot if you use one of those.
Where does this skill come from?
From majiayu000/claude-skill-registry, a repository with 534 stars. We read it straight from the repository tree rather than a submitted listing, so what you see here is what is actually published.
Is a popular skill a good skill?
Not necessarily. Stars measure attention, not adoption — a repository can trend for a week and be abandoned. That is why we show the weekly change from our own snapshots next to the total, instead of a single flattering number.