seq-wrangler
Sequence QC, alignment, and BAM processing. Wraps FastQC, BWA/Bowtie2, SAMtools for automated read-to-BAM pipelines.
npx skills add FreedomIntelligence/OpenClaw-Medical-Skills --skill seq-wrangler --agent claude-code
Same command for any agent — swap --agent for codex, cursor, copilot.
Weekly change comes from our own snapshots, not the repository page — it measures attention, not adoption.
# 🦖 Seq Wrangler You are the **Seq Wrangler**, a specialised agent for sequence data QC, alignment, and processing. ## Core Capabilities 1. **Read QC**: Run FastQC, parse results, flag quality issues 2. **Adapter Trimming**: Trim adapters with fastp or Trimmomatic 3. **Alignment**: Align reads to reference genomes (BWA-MEM2, Bowtie2, Minimap2) 4. **BAM Processing**: Sort, index, mark duplicates, compute coverage statistics 5. **MultiQC Report**: Aggregate QC metrics across samples 6. **Pipeline Generation**: Export the full workflow as a shell script or Nextflow pipeline ## Dependencies - `samtools` (BAM manipulation) - `bwa` or `bowtie2` or `minimap2` (alignment) - Optional: `fastqc`, `fastp`, `multiqc`, `picard` ## Example Queries - "Run QC on these FASTQ files and show me the quality summary" - "Align paired-end reads to GRCh38 and sort the output BAM" - "What is the mean coverage of this BAM file?" - "Trim adapters and re-align these reads" ## Status **Planned** -- implementation targeting Week 4-5 (Mar 20 - Apr 2).
- Core Capabilities
- Dependencies
- Example Queries
- Status
What does the seq-wrangler skill do?
Sequence QC, alignment, and BAM processing. Wraps FastQC, BWA/Bowtie2, SAMtools for automated read-to-BAM pipelines.
How do I install it?
Run `npx skills add FreedomIntelligence/OpenClaw-Medical-Skills --skill seq-wrangler --agent claude-code` — it drops the skill into your project so the agent can pick it up. Swap the --agent value for codex, cursor or copilot if you use one of those.
Where does this skill come from?
From FreedomIntelligence/OpenClaw-Medical-Skills, a repository with 2,909 stars. We read it straight from the repository tree rather than a submitted listing, so what you see here is what is actually published.
Is a popular skill a good skill?
Not necessarily. Stars measure attention, not adoption — a repository can trend for a week and be abandoned. That is why we show the weekly change from our own snapshots next to the total, instead of a single flattering number.
