screploading
Load single-cell TCR-seq or scBCR-seq data from various formats into a scRepertoire-compatible object. This process reads VDJ (variable, diversity, joining) receptor contig data from multiple single-cell sequencing platforms and prepares it for integration with scRNA-seq data.
npx skills add majiayu000/claude-skill-registry --skill screploading --agent claude-code
Same command for any agent — swap --agent for codex, cursor, copilot.
Weekly change comes from our own snapshots, not the repository page — it measures attention, not adoption.
# ScRepLoading Process Configuration ## Purpose Load single-cell TCR-seq or scBCR-seq data from various formats into a scRepertoire-compatible object. This process reads VDJ (variable, diversity, joining) receptor contig data from multiple single-cell sequencing platforms and prepares it for integration with scRNA-seq data. ## When to Use - **When analyzing scTCR-seq or scBCR-seq data** alongside scRNA-seq - **Required for TCR/BCR clonotype analysis** (CDR3 clustering, clone expansion, TESSA analysis) - **Enables integration** of immune receptor information with single-cell expression data - **Supports multiple sequencing platforms**: 10x Genomics, AIRR, BD, Dandelion, Immcantation, MiXCR, ParseBio, TRUST4, WAT3R, Omniscope **Important**: This process is automatically enabled when your sample info file contains `TCRData` or `BCRData` columns. ## Configuration Structure ### Process Enablement ```toml [ScRepLoading] cache = true # Enable caching (default: true) ``` ### Input Specification ```toml [ScRepLoading.in] # Type: file # Required: yes # Description: Sample metadata file (tab-delimited) with TCR/BCR data paths metafile = "path/to/sample_info.txt" ``` **Required input file colu
- Purpose
- When to Use
- Configuration Structure
- Process Enablement
- Input Specification
- Environment Variables
- Configuration Examples
- Minimal Configuration (10x TCR Data)
- Single Sample with Format Specification
- Multi-Sample BCR Analysis with Clustering
- Non-10x Format (AIRR)
- TRUST4 Format
- Common Patterns
- Pattern 1: 10x Genomics TCR Data (Most Common)
What does the screploading skill do?
Load single-cell TCR-seq or scBCR-seq data from various formats into a scRepertoire-compatible object. This process reads VDJ (variable, diversity, joining) receptor contig data from multiple single-cell sequencing platforms and prepares it for integration with scRNA-seq data.
How do I install it?
Run `npx skills add majiayu000/claude-skill-registry --skill screploading --agent claude-code` — it drops the skill into your project so the agent can pick it up. Swap the --agent value for codex, cursor or copilot if you use one of those.
Where does this skill come from?
From majiayu000/claude-skill-registry, a repository with 534 stars. We read it straight from the repository tree rather than a submitted listing, so what you see here is what is actually published.
Is a popular skill a good skill?
Not necessarily. Stars measure attention, not adoption — a repository can trend for a week and be abandoned. That is why we show the weekly change from our own snapshots next to the total, instead of a single flattering number.