sanger-chromatogram-qa
Assess Sanger sequencing chromatogram quality, detect mixed peaks, confirm variants, and flag samples requiring repeat sequencing.
npx skills add majiayu000/claude-skill-registry --skill sanger-chromatogram-qa --agent claude-code
Same command for any agent — swap --agent for codex, cursor, copilot.
Weekly change comes from our own snapshots, not the repository page — it measures attention, not adoption.
# Sanger Chromatogram QA Quality assessment for Sanger sequencing chromatograms: mixed-peak detection, variant confirmation, and repeat-sequencing recommendations. ## Input Validation This skill accepts: `.ab1` chromatogram files paired with a reference sequence, optionally with a variant position, for Sanger sequencing quality assessment. If the request does not involve Sanger chromatogram QA — for example, asking to analyze NGS FASTQ files, perform de-novo assembly, or interpret mass spectrometry data — do not proceed. Instead respond: > "sanger-chromatogram-qa is designed to assess Sanger sequencing chromatogram quality. Your request appears to be outside this scope. Please provide an .ab1 file and reference sequence, or use a more appropriate tool for your task. For NGS FASTQ analysis, consider FastQC or a dedicated variant calling pipeline." ## When to Use - Mutation verification after Sanger sequencing - Clone confirmation (correct insert, correct orientation) - Genotyping QC (heterozygous vs homozygous calls) - SNP validation against a reference sequence ## Quick Check ```bash python -m py_compile scripts/main.py python scripts/main.py --help python scripts/main.py --demo ``
- Input Validation
- When to Use
- Quick Check
- Workflow
- Parameters
- Returns
- Fallback Template
- Output Requirements
- Error Handling
- Response Template
- Risk Assessment
- Prerequisites
python -m py_compile scripts/main.py python scripts/main.py --help python scripts/main.py --demo pip install -r requirements.txt
What does the sanger-chromatogram-qa skill do?
Assess Sanger sequencing chromatogram quality, detect mixed peaks, confirm variants, and flag samples requiring repeat sequencing.
How do I install it?
Run `npx skills add majiayu000/claude-skill-registry --skill sanger-chromatogram-qa --agent claude-code` — it drops the skill into your project so the agent can pick it up. Swap the --agent value for codex, cursor or copilot if you use one of those.
Where does this skill come from?
From majiayu000/claude-skill-registry, a repository with 534 stars. We read it straight from the repository tree rather than a submitted listing, so what you see here is what is actually published.
Is a popular skill a good skill?
Not necessarily. Stars measure attention, not adoption — a repository can trend for a week and be abandoned. That is why we show the weekly change from our own snapshots next to the total, instead of a single flattering number.