Agent skill · Databases

reactome-database

Query Reactome REST API for pathway analysis, enrichment, gene-pathway mapping, disease pathways, molecular interactions, expression analysis, for systems biology studies.

FreedomIntelligencegithub.com/FreedomIntelligenceGitHub ↗
claude-codeships scripts
Install
npx skills add FreedomIntelligence/OpenClaw-Medical-Skills --skill reactome-database --agent claude-code

Same command for any agent — swap --agent for codex, cursor, copilot.

Facts
Files in the skill folder: 3
SKILL.md size: 8 KB
Bundled scripts: yes
Path: skills/reactome-database/SKILL.md
Open the folder on GitHub →
Where it comes from
Stars: 2,909
Language: Python
Read our review of the source →

Weekly change comes from our own snapshots, not the repository page — it measures attention, not adoption.

From the SKILL.md

# Reactome Database ## Overview Reactome is a free, open-source, curated pathway database with 2,825+ human pathways. Query biological pathways, perform overrepresentation and expression analysis, map genes to pathways, explore molecular interactions via REST API and Python client for systems biology research. ## When to Use This Skill This skill should be used when: - Performing pathway enrichment analysis on gene or protein lists - Analyzing gene expression data to identify relevant biological pathways - Querying specific pathway information, reactions, or molecular interactions - Mapping genes or proteins to biological pathways and processes - Exploring disease-related pathways and mechanisms - Visualizing analysis results in the Reactome Pathway Browser - Conducting comparative pathway analysis across species ## Core Capabilities Reactome provides two main API services and a Python client library: ### 1. Content Service - Data Retrieval Query and retrieve biological pathway data, molecular interactions, and entity information. **Common operations:** - Retrieve pathway information and hierarchies - Query specific entities (proteins, reactions, complexes) - Get participating mole

What's inside
Steps it walks through
  1. Overview
  2. When to Use This Skill
  3. Core Capabilities
  4. 1. Content Service - Data Retrieval
  5. 2. Analysis Service - Pathway Analysis
  6. 3. reactome2py Python Package
  7. Querying Pathway Data
  8. Using Content Service REST API
  9. Using reactome2py Package
  10. Performing Pathway Analysis
  11. Overrepresentation Analysis
  12. Expression Data Analysis
  13. Species Projection
  14. Visualizing Results
Ships with 2 files
  • references/api_reference.md
  • scripts/reactome_query.py
Commands it runs
uv pip install reactome2py
Query pathway information
python scripts/reactome_query.py query R-HSA-69278
Perform overrepresentation analysis
python scripts/reactome_query.py analyze gene_list.txt
Get database version
python scripts/reactome_query.py version
More from OpenClaw-Medical-Skills
All skills →
About this skill
What does the reactome-database skill do?

Query Reactome REST API for pathway analysis, enrichment, gene-pathway mapping, disease pathways, molecular interactions, expression analysis, for systems biology studies.

How do I install it?

Run `npx skills add FreedomIntelligence/OpenClaw-Medical-Skills --skill reactome-database --agent claude-code` — it drops the skill into your project so the agent can pick it up. Swap the --agent value for codex, cursor or copilot if you use one of those.

Where does this skill come from?

From FreedomIntelligence/OpenClaw-Medical-Skills, a repository with 2,909 stars. We read it straight from the repository tree rather than a submitted listing, so what you see here is what is actually published.

Is a popular skill a good skill?

Not necessarily. Stars measure attention, not adoption — a repository can trend for a week and be abandoned. That is why we show the weekly change from our own snapshots next to the total, instead of a single flattering number.

Keep going