ligand-exchange-protocol-manager
Surface chemistry skill for managing ligand exchange reactions, bioconjugation protocols, and functional group quantification
npx skills add a5c-ai/babysitter --skill ligand-exchange-protocol-manager --agent claude-code
Same command for any agent — swap --agent for codex, cursor, copilot.
Weekly change comes from our own snapshots, not the repository page — it measures attention, not adoption.
# Ligand Exchange Protocol Manager ## Purpose The Ligand Exchange Protocol Manager skill provides systematic management of surface functionalization reactions for nanoparticles, enabling controlled ligand exchange, bioconjugation, and quantification of surface functional groups. ## Capabilities - Ligand exchange reaction design - Bioconjugation chemistry selection - Click chemistry protocols - Functional group quantification (TNBS, Ellman's) - Conjugation efficiency optimization - Surface coverage calculation ## Usage Guidelines ### Ligand Exchange Design 1. **Chemistry Selection** - Match incoming ligand affinity - Consider exchange kinetics - Optimize solvent system 2. **Bioconjugation Protocols** - EDC/NHS for carboxyl-amine coupling - Maleimide-thiol for cysteine targeting - Click chemistry for orthogonal conjugation 3. **Surface Coverage Quantification** - UV-Vis for chromophoric ligands - TGA for organic content - XPS for elemental analysis ## Process Integration - Nanomaterial Surface Functionalization Pipeline - Nanoparticle Drug Delivery System Development - Nanosensor Development and Validation Pipeline ## Input Schema ```json { "nanoparticle_type": "string", "current_lig
- Purpose
- Capabilities
- Usage Guidelines
- Ligand Exchange Design
- Process Integration
- Input Schema
- Output Schema
What does the ligand-exchange-protocol-manager skill do?
Surface chemistry skill for managing ligand exchange reactions, bioconjugation protocols, and functional group quantification
How do I install it?
Run `npx skills add a5c-ai/babysitter --skill ligand-exchange-protocol-manager --agent claude-code` — it drops the skill into your project so the agent can pick it up. Swap the --agent value for codex, cursor or copilot if you use one of those.
Where does this skill come from?
From a5c-ai/babysitter, a repository with 1,642 stars. We read it straight from the repository tree rather than a submitted listing, so what you see here is what is actually published.
Is a popular skill a good skill?
Not necessarily. Stars measure attention, not adoption — a repository can trend for a week and be abandoned. That is why we show the weekly change from our own snapshots next to the total, instead of a single flattering number.