interpro-database
Query InterPro for protein family, domain, and functional site annotations. Integrates Pfam, PANTHER, PRINTS, SMART, SUPERFAMILY, and 11 other member databases. Use for protein function prediction, domain architecture analysis, evolutionary classification, and GO term mapping.
npx skills add LeonChaoX/qinyan-academic-skills --skill interpro-database --agent claude-code
Same command for any agent — swap --agent for codex, cursor, copilot.
Weekly change comes from our own snapshots, not the repository page — it measures attention, not adoption.
# InterPro Database ## Overview InterPro (https://www.ebi.ac.uk/interpro/) is a comprehensive resource for protein family and domain classification maintained by EMBL-EBI. It integrates signatures from 13 member databases including Pfam, PANTHER, PRINTS, ProSite, SMART, TIGRFAM, SUPERFAMILY, CDD, and others, providing a unified view of protein functional annotations for over 100 million protein sequences. InterPro classifies proteins into: - **Families**: Groups of proteins sharing common ancestry and function - **Domains**: Independently folding structural/functional units - **Homologous superfamilies**: Structurally similar protein regions - **Repeats**: Short tandem sequences - **Sites**: Functional sites (active, binding, PTM) **Key resources:** - InterPro website: https://www.ebi.ac.uk/interpro/ - REST API: https://www.ebi.ac.uk/interpro/api/ - API documentation: https://github.com/ProteinsWebTeam/interpro7-api/blob/master/docs/ - Python client: via `requests` ## When to Use This Skill Use InterPro when: - **Protein function prediction**: What function(s) does an uncharacterized protein likely have? - **Domain architecture**: What domains make up a protein, and in what order?
- Overview
- When to Use This Skill
- Core Capabilities
- 1. InterPro REST API
- 2. Look Up a Protein
- 3. Get Specific InterPro Entry
- 4. Search Proteins by InterPro Entry
- 5. Domain Architecture
- 6. GO Term Mapping
- 7. Batch Protein Lookup
- 8. Search by Text or Taxonomy
- Query Workflows
- Workflow 1: Characterize an Unknown Protein
- Workflow 2: Find All Members of a Protein Family
What does the interpro-database skill do?
Query InterPro for protein family, domain, and functional site annotations. Integrates Pfam, PANTHER, PRINTS, SMART, SUPERFAMILY, and 11 other member databases. Use for protein function prediction, domain architecture analysis, evolutionary classification, and GO term mapping.
How do I install it?
Run `npx skills add LeonChaoX/qinyan-academic-skills --skill interpro-database --agent claude-code` — it drops the skill into your project so the agent can pick it up. Swap the --agent value for codex, cursor or copilot if you use one of those.
Where does this skill come from?
From LeonChaoX/qinyan-academic-skills, a repository with 759 stars. We read it straight from the repository tree rather than a submitted listing, so what you see here is what is actually published.
Is a popular skill a good skill?
Not necessarily. Stars measure attention, not adoption — a repository can trend for a week and be abandoned. That is why we show the weekly change from our own snapshots next to the total, instead of a single flattering number.