indication-dossier
Generate a therapeutic indication dossier. Covers the patient population, epidemiology, disease biology, standard of care, regulatory precedent, and landmark clinical trials.
Profile →npx skills add xuzhougeng/wisp-science --skill indication-dossier --agent claude-code
Same command for any agent — swap --agent for codex, cursor, copilot.
Weekly change comes from our own snapshots, not the repository page — it measures attention, not adoption.
# Indication Dossier Produces a structured research dossier on a single indication, framed as a patient population: who they are, what's wrong, how they're treated today, and how clinical trials can be designed to help them. Runs as five phases that write resumable waypoint files; after a brief identity check at the end of Phase 1, the remaining phases run straight through. ## Framing **Think of an indication as a patient population.** Frame everything from the patient perspective: "Who are these patients?" not "What is this disease?"; "How are these patients identified and managed?" not "What causes this condition?"; population nesting: "all patients in {child} are patients in {parent}". Some indications don't map to ICD codes or standard disease definitions: "immunosenescence" is a biological state, not a billable diagnosis; "ageing" is not an FDA-accepted indication; "GLP-1 induced sarcopenia" is an iatrogenic population. Note these distinctions explicitly. They matter for regulatory path and trial design. ## Inputs - **`indication`** (required) — indication name (e.g., "sarcopenia", "idiopathic pulmonary fibrosis"). - **`additional_context`** (optional) — areas to focus on, par
- Framing
- Inputs
- Tools this skill expects
- Output layout
- Before starting
- Workflow
- Phase 1 — Meta initialization
- Phase 2 — Epidemiology research
- Phase 3 — Biology & standard-of-care research
- Phase 4 — Regulatory & trials research
- Phase 5 — Synthesis
- Resuming
What does the indication-dossier skill do?
Generate a therapeutic indication dossier. Covers the patient population, epidemiology, disease biology, standard of care, regulatory precedent, and landmark clinical trials.
How do I install it?
Run `npx skills add xuzhougeng/wisp-science --skill indication-dossier --agent claude-code` — it drops the skill into your project so the agent can pick it up. Swap the --agent value for codex, cursor or copilot if you use one of those.
Where does this skill come from?
From xuzhougeng/wisp-science, a repository with 895 stars. We read it straight from the repository tree rather than a submitted listing, so what you see here is what is actually published.
Is a popular skill a good skill?
Not necessarily. Stars measure attention, not adoption — a repository can trend for a week and be abandoned. That is why we show the weekly change from our own snapshots next to the total, instead of a single flattering number.