Agent skill · Databases

brenda-database

Access BRENDA enzyme database via SOAP API. Retrieve kinetic parameters (Km, kcat), reaction equations, organism data, and substrate-specific enzyme information for biochemical research and metabolic pathway analysis.

FreedomIntelligencegithub.com/FreedomIntelligenceGitHub ↗
claude-codeships scripts
Install
npx skills add FreedomIntelligence/OpenClaw-Medical-Skills --skill brenda-database --agent claude-code

Same command for any agent — swap --agent for codex, cursor, copilot.

Facts
Files in the skill folder: 5
SKILL.md size: 22 KB
Bundled scripts: yes
Path: skills/brenda-database/SKILL.md
Open the folder on GitHub →
Where it comes from
Stars: 2,909
Language: Python
Read our review of the source →

Weekly change comes from our own snapshots, not the repository page — it measures attention, not adoption.

From the SKILL.md

# BRENDA Database ## Overview BRENDA (BRaunschweig ENzyme DAtabase) is the world's most comprehensive enzyme information system, containing detailed enzyme data from scientific literature. Query kinetic parameters (Km, kcat), reaction equations, substrate specificities, organism information, and optimal conditions for enzymes using the official SOAP API. Access over 45,000 enzymes with millions of kinetic data points for biochemical research, metabolic engineering, and enzyme discovery. ## When to Use This Skill This skill should be used when: - Searching for enzyme kinetic parameters (Km, kcat, Vmax) - Retrieving reaction equations and stoichiometry - Finding enzymes for specific substrates or reactions - Comparing enzyme properties across different organisms - Investigating optimal pH, temperature, and conditions - Accessing enzyme inhibition and activation data - Supporting metabolic pathway reconstruction and retrosynthesis - Performing enzyme engineering and optimization studies - Analyzing substrate specificity and cofactor requirements ## Core Capabilities ### 1. Kinetic Parameter Retrieval Access comprehensive kinetic data for enzymes: **Get Km Values by EC Number**: ```pyt

What's inside
Steps it walks through
  1. Overview
  2. When to Use This Skill
  3. Core Capabilities
  4. 1. Kinetic Parameter Retrieval
  5. 2. Reaction Information
  6. 3. Enzyme Discovery
  7. 4. Organism-Specific Enzyme Data
  8. 5. Environmental Parameters
  9. 6. Substrate Specificity
  10. 7. Inhibition and Activation
  11. 8. Enzyme Engineering Support
  12. 9. Kinetic Modeling
  13. Installation Requirements
  14. Authentication Setup
Ships with 4 files
  • references/api_reference.md
  • scripts/brenda_queries.py
  • scripts/brenda_visualization.py
  • scripts/enzyme_pathway_builder.py
Commands it runs
uv pip install zeep requests pandas matplotlib seaborn
export BRENDA_EMAIL="your.email@example.com"
export BRENDA_PASSWORD="your_brenda_password"
More from OpenClaw-Medical-Skills
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About this skill
What does the brenda-database skill do?

Access BRENDA enzyme database via SOAP API. Retrieve kinetic parameters (Km, kcat), reaction equations, organism data, and substrate-specific enzyme information for biochemical research and metabolic pathway analysis.

How do I install it?

Run `npx skills add FreedomIntelligence/OpenClaw-Medical-Skills --skill brenda-database --agent claude-code` — it drops the skill into your project so the agent can pick it up. Swap the --agent value for codex, cursor or copilot if you use one of those.

Where does this skill come from?

From FreedomIntelligence/OpenClaw-Medical-Skills, a repository with 2,909 stars. We read it straight from the repository tree rather than a submitted listing, so what you see here is what is actually published.

Is a popular skill a good skill?

Not necessarily. Stars measure attention, not adoption — a repository can trend for a week and be abandoned. That is why we show the weekly change from our own snapshots next to the total, instead of a single flattering number.

Keep going