Agent skill · Data & Analytics

bio-single-cell-metabolite-communication

Analyze metabolite-mediated cell-cell communication using MeboCost for metabolic signaling inference between cell types. Predict metabolite secretion and sensing patterns from scRNA-seq data. Use when studying metabolic crosstalk between cell populations or metabolite-receptor interactions.

FreedomIntelligencegithub.com/FreedomIntelligenceGitHub ↗
claude-codeships scripts
Install
npx skills add FreedomIntelligence/OpenClaw-Medical-Skills --skill bio-single-cell-metabolite-communication --agent claude-code

Same command for any agent — swap --agent for codex, cursor, copilot.

Facts
Files in the skill folder: 3
SKILL.md size: 8 KB
Bundled scripts: yes
Path: skills/bio-single-cell-metabolite-communication/SKILL.md
Open the folder on GitHub →
Where it comes from
Stars: 2,909
Language: Python
Read our review of the source →

Weekly change comes from our own snapshots, not the repository page — it measures attention, not adoption.

From the SKILL.md

## Version Compatibility Reference examples tested with: matplotlib 3.8+, scanpy 1.10+ Before using code patterns, verify installed versions match. If versions differ: - Python: `pip show <package>` then `help(module.function)` to check signatures If code throws ImportError, AttributeError, or TypeError, introspect the installed package and adapt the example to match the actual API rather than retrying. # Metabolite-Mediated Cell Communication **"Analyze metabolic crosstalk between cell types"** → Predict metabolite secretion-sensing interactions between cell populations based on enzyme and transporter expression patterns. - Python: `mebocost.MeboCost(adata, groupby='cell_type')` → `run_mebocost()` ## MeboCost Overview MeboCost infers metabolite-mediated communication by: 1. Predicting metabolite secretion from enzyme expression 2. Identifying metabolite-sensing receptors 3. Computing communication scores between cell types ## Basic Workflow **Goal:** Infer metabolite-mediated cell-cell communication from scRNA-seq data by predicting which cell types secrete and sense specific metabolites. **Approach:** Initialize a MeboCost object from an AnnData with cell type annotations, run pe

What's inside
Steps it walks through
  1. Version Compatibility
  2. MeboCost Overview
  3. Basic Workflow
  4. Prepare Data
  5. Run Communication Analysis
  6. Analyze Results
  7. Visualization
  8. Compare Conditions
  9. Metabolite Categories
  10. Related Skills
Ships with 2 files
  • examples/metabolite_communication.py
  • usage-guide.md
More from OpenClaw-Medical-Skills
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About this skill
What does the bio-single-cell-metabolite-communication skill do?

Analyze metabolite-mediated cell-cell communication using MeboCost for metabolic signaling inference between cell types. Predict metabolite secretion and sensing patterns from scRNA-seq data. Use when studying metabolic crosstalk between cell populations or metabolite-receptor interactions.

How do I install it?

Run `npx skills add FreedomIntelligence/OpenClaw-Medical-Skills --skill bio-single-cell-metabolite-communication --agent claude-code` — it drops the skill into your project so the agent can pick it up. Swap the --agent value for codex, cursor or copilot if you use one of those.

Where does this skill come from?

From FreedomIntelligence/OpenClaw-Medical-Skills, a repository with 2,909 stars. We read it straight from the repository tree rather than a submitted listing, so what you see here is what is actually published.

Is a popular skill a good skill?

Not necessarily. Stars measure attention, not adoption — a repository can trend for a week and be abandoned. That is why we show the weekly change from our own snapshots next to the total, instead of a single flattering number.

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