Agent skill · Data & Analytics

bio-single-cell-cell-communication

Infer cell-cell communication networks from scRNA-seq data using CellChat, NicheNet, and LIANA for ligand-receptor interaction analysis. Use when inferring ligand-receptor interactions between cell types.

FreedomIntelligencegithub.com/FreedomIntelligenceGitHub ↗
claude-codeships scripts
Install
npx skills add FreedomIntelligence/OpenClaw-Medical-Skills --skill bio-single-cell-cell-communication --agent claude-code

Same command for any agent — swap --agent for codex, cursor, copilot.

Facts
Files in the skill folder: 4
SKILL.md size: 8 KB
Bundled scripts: yes
Path: skills/bio-single-cell-cell-communication/SKILL.md
Open the folder on GitHub →
Where it comes from
Stars: 2,909
Language: Python
Read our review of the source →

Weekly change comes from our own snapshots, not the repository page — it measures attention, not adoption.

From the SKILL.md

## Version Compatibility Reference examples tested with: ggplot2 3.5+, scanpy 1.10+ Before using code patterns, verify installed versions match. If versions differ: - Python: `pip show <package>` then `help(module.function)` to check signatures - R: `packageVersion('<pkg>')` then `?function_name` to verify parameters If code throws ImportError, AttributeError, or TypeError, introspect the installed package and adapt the example to match the actual API rather than retrying. # Cell-Cell Communication Analysis **"Infer cell-cell communication from my scRNA-seq data"** → Predict ligand-receptor interactions between cell types and visualize intercellular signaling networks. - R: `CellChat::createCellChat()` → `computeCommunProb()` → `netAnalysis()` - Python: `liana.method.cellchat()` (LIANA framework) ## CellChat (R) **Goal:** Infer and quantify intercellular communication networks from scRNA-seq data using curated ligand-receptor databases. **Approach:** Create a CellChat object from a Seurat object with cell type labels, select a signaling database subset, identify overexpressed ligands/receptors, compute communication probabilities using the trimean method, then aggregate into pathwa

What's inside
Steps it walks through
  1. Version Compatibility
  2. CellChat (R)
  3. CellChat Visualization
  4. CellChat Pathway Analysis
  5. Compare Conditions (CellChat)
  6. NicheNet (R)
  7. NicheNet Visualization
  8. LIANA (Python)
  9. LIANA with Tensor Decomposition
  10. Related Skills
Ships with 3 files
  • examples/cellchat_analysis.R
  • examples/liana_analysis.py
  • usage-guide.md
More from OpenClaw-Medical-Skills
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About this skill
What does the bio-single-cell-cell-communication skill do?

Infer cell-cell communication networks from scRNA-seq data using CellChat, NicheNet, and LIANA for ligand-receptor interaction analysis. Use when inferring ligand-receptor interactions between cell types.

How do I install it?

Run `npx skills add FreedomIntelligence/OpenClaw-Medical-Skills --skill bio-single-cell-cell-communication --agent claude-code` — it drops the skill into your project so the agent can pick it up. Swap the --agent value for codex, cursor or copilot if you use one of those.

Where does this skill come from?

From FreedomIntelligence/OpenClaw-Medical-Skills, a repository with 2,909 stars. We read it straight from the repository tree rather than a submitted listing, so what you see here is what is actually published.

Is a popular skill a good skill?

Not necessarily. Stars measure attention, not adoption — a repository can trend for a week and be abandoned. That is why we show the weekly change from our own snapshots next to the total, instead of a single flattering number.

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