bio-proteomics-spectral-libraries
Build, manage, and search spectral libraries for proteomics. Use when creating or working with spectral libraries for DIA analysis. Covers DDA-based library generation, predicted libraries (Prosit, DeepLC), and library formats.
npx skills add FreedomIntelligence/OpenClaw-Medical-Skills --skill bio-proteomics-spectral-libraries --agent claude-code
Same command for any agent — swap --agent for codex, cursor, copilot.
Weekly change comes from our own snapshots, not the repository page — it measures attention, not adoption.
## Version Compatibility Reference examples tested with: matplotlib 3.8+, pandas 2.2+ Before using code patterns, verify installed versions match. If versions differ: - Python: `pip show <package>` then `help(module.function)` to check signatures - CLI: `<tool> --version` then `<tool> --help` to confirm flags If code throws ImportError, AttributeError, or TypeError, introspect the installed package and adapt the example to match the actual API rather than retrying. # Spectral Library Management **"Build a spectral library for DIA analysis"** → Create, filter, and manage spectral libraries from DDA experiments or predicted spectra for use in DIA quantification workflows. - CLI: `spectrast` (TPP) for consensus library building from search results - CLI: Prosit/DeepLC for deep learning-predicted spectral libraries - Python: `pandas` for library format conversion and quality filtering ## Build Library from DDA Data ### SpectraST (TPP) ```bash # Build library from search results spectrast -cNlibrary.splib -cAC search_results.pep.xml # Filter library for quality spectrast -cNfiltered.splib -cAQ library.splib # Convert to other formats spectrast -cNlibrary.tsv -cM library.splib ``` ### Ea
- Version Compatibility
- Build Library from DDA Data
- SpectraST (TPP)
- EasyPQP (Skyline/OpenMS)
- EncyclopeDIA (Walnut)
- Predicted Libraries
- Prosit (Deep Learning)
- DeepLC Retention Time Prediction
- MS2PIP Fragmentation Prediction
- Library Formats
- DIA-NN TSV Format
- OpenSWATH TSV Format
- Spectronaut Library Format
- Library QC
Build library from search results spectrast -cNlibrary.splib -cAC search_results.pep.xml Filter library for quality spectrast -cNfiltered.splib -cAQ library.splib Convert to other formats spectrast -cNlibrary.tsv -cM library.splib easypqp library \ Convert to TSV format easypqp convert \ Build chromatogram library from DIA
What does the bio-proteomics-spectral-libraries skill do?
Build, manage, and search spectral libraries for proteomics. Use when creating or working with spectral libraries for DIA analysis. Covers DDA-based library generation, predicted libraries (Prosit, DeepLC), and library formats.
How do I install it?
Run `npx skills add FreedomIntelligence/OpenClaw-Medical-Skills --skill bio-proteomics-spectral-libraries --agent claude-code` — it drops the skill into your project so the agent can pick it up. Swap the --agent value for codex, cursor or copilot if you use one of those.
Where does this skill come from?
From FreedomIntelligence/OpenClaw-Medical-Skills, a repository with 2,909 stars. We read it straight from the repository tree rather than a submitted listing, so what you see here is what is actually published.
Is a popular skill a good skill?
Not necessarily. Stars measure attention, not adoption — a repository can trend for a week and be abandoned. That is why we show the weekly change from our own snapshots next to the total, instead of a single flattering number.