bio-proteomics-protein-inference
Protein grouping and inference from peptide identifications. Use when resolving protein ambiguity from shared peptides. Handles protein groups and protein-level FDR control using parsimony and probabilistic approaches.
npx skills add FreedomIntelligence/OpenClaw-Medical-Skills --skill bio-proteomics-protein-inference --agent claude-code
Same command for any agent — swap --agent for codex, cursor, copilot.
Weekly change comes from our own snapshots, not the repository page — it measures attention, not adoption.
## Version Compatibility Reference examples tested with: pyOpenMS 3.1+ Before using code patterns, verify installed versions match. If versions differ: - Python: `pip show <package>` then `help(module.function)` to check signatures - R: `packageVersion("<pkg>")` then `?function_name` to verify parameters If code throws ImportError, AttributeError, or TypeError, introspect the installed package and adapt the example to match the actual API rather than retrying. # Protein Inference **"Resolve protein groups from my peptide identifications"** → Group peptide-spectrum matches into protein groups, resolving shared-peptide ambiguity using parsimony or probabilistic methods, then apply protein-level FDR. - Python: `pyopenms.ProteinInference()` for parsimony-based grouping - R: Bioconductor protein inference workflows ## The Protein Inference Problem Peptides can map to multiple proteins (shared peptides), making protein identification ambiguous. ```python # Example: Peptide mapping peptide_to_proteins = { 'PEPTIDEK': ['P12345', 'P67890'], # Shared between paralogs 'UNIQUER': ['P12345'], # Unique to P12345 'ANOTHERONE': ['P12345'], # Unique to P12345 'SHAREDK': ['P67890', 'P11111'], # Shar
- Version Compatibility
- The Protein Inference Problem
- Parsimony Principle
- Protein Groups
- pyOpenMS Protein Inference
- R: Protein Inference with ProteinInference
- Protein-Level FDR
- Related Skills
What does the bio-proteomics-protein-inference skill do?
Protein grouping and inference from peptide identifications. Use when resolving protein ambiguity from shared peptides. Handles protein groups and protein-level FDR control using parsimony and probabilistic approaches.
How do I install it?
Run `npx skills add FreedomIntelligence/OpenClaw-Medical-Skills --skill bio-proteomics-protein-inference --agent claude-code` — it drops the skill into your project so the agent can pick it up. Swap the --agent value for codex, cursor or copilot if you use one of those.
Where does this skill come from?
From FreedomIntelligence/OpenClaw-Medical-Skills, a repository with 2,909 stars. We read it straight from the repository tree rather than a submitted listing, so what you see here is what is actually published.
Is a popular skill a good skill?
Not necessarily. Stars measure attention, not adoption — a repository can trend for a week and be abandoned. That is why we show the weekly change from our own snapshots next to the total, instead of a single flattering number.