bio-metabolomics-normalization-qc
Quality control and normalization for metabolomics data. Covers QC-based correction, batch effect removal, and data transformation methods. Use when correcting technical variation in metabolomics data before statistical analysis.
npx skills add FreedomIntelligence/OpenClaw-Medical-Skills --skill bio-metabolomics-normalization-qc --agent claude-code
Same command for any agent — swap --agent for codex, cursor, copilot.
Weekly change comes from our own snapshots, not the repository page — it measures attention, not adoption.
## Version Compatibility Reference examples tested with: xcms 4.0+ Before using code patterns, verify installed versions match. If versions differ: - R: `packageVersion('<pkg>')` then `?function_name` to verify parameters If code throws ImportError, AttributeError, or TypeError, introspect the installed package and adapt the example to match the actual API rather than retrying. # Metabolomics Normalization and QC ## Load and Inspect Data **Goal:** Load the feature table and sample metadata, separating QC and biological samples for downstream processing. **Approach:** Read CSV files, partition by sample type, and assess missing value prevalence. **"Normalize my metabolomics data and correct for batch effects"** → Apply QC-based signal correction, handle missing values, transform intensities, and assess normalization quality via RSD and PCA. ```r library(tidyverse) library(pcaMethods) # Load feature table (samples x features) data <- read.csv('feature_table.csv', row.names = 1) sample_info <- read.csv('sample_info.csv') # Separate QC samples qc_samples <- sample_info$sample_name[sample_info$sample_type == 'QC'] bio_samples <- sample_info$sample_name[sample_info$sample_type != 'QC'] d
- Version Compatibility
- Load and Inspect Data
- QC-Based Normalization (QC-RSC)
- Total Ion Current (TIC) Normalization
- Probabilistic Quotient Normalization (PQN)
- Batch Correction (ComBat)
- Missing Value Handling
- Data Transformation
- QC Assessment
- Quality Report
- Related Skills
What does the bio-metabolomics-normalization-qc skill do?
Quality control and normalization for metabolomics data. Covers QC-based correction, batch effect removal, and data transformation methods. Use when correcting technical variation in metabolomics data before statistical analysis.
How do I install it?
Run `npx skills add FreedomIntelligence/OpenClaw-Medical-Skills --skill bio-metabolomics-normalization-qc --agent claude-code` — it drops the skill into your project so the agent can pick it up. Swap the --agent value for codex, cursor or copilot if you use one of those.
Where does this skill come from?
From FreedomIntelligence/OpenClaw-Medical-Skills, a repository with 2,909 stars. We read it straight from the repository tree rather than a submitted listing, so what you see here is what is actually published.
Is a popular skill a good skill?
Not necessarily. Stars measure attention, not adoption — a repository can trend for a week and be abandoned. That is why we show the weekly change from our own snapshots next to the total, instead of a single flattering number.
