At Origami Therapeutics, Dr. Hoffman is creating a new approach to drug discovery for neurodegenerative diseases. Prior to Origami, she was a Research & Development executive at Vertex Pharmaceuticals, Amgen and Eli Lilly. She has made major contributions to >30 clinical programs in neurology, pain and psychiatry and to four marketed drugs for Cystic Fibrosis. Dr. Hoffman received her A.B. in Molecular Biology from Wellesley College and a Ph.D. in Cell Biology from the Johns Hopkins University.